Globin gene transcripts can utilize histone gene 3′ end processing signals
نویسندگان
چکیده
منابع مشابه
RNA processing of beta-globin transcripts containing 5' flanking and structural gene sequences.
RNA species have been identified in murine erythroid cells which contain both 5' flanking and structural gene sequences from the beta maj globin gene. Two nonpolyadenylated RNA transcripts, average 3700 and 1800-1900 nucleotides long, were identified by denaturing agarose gel electrophoresis and were found to hybridize to both 5' and 3' beta maj globin flanking sequences. This finding suggests ...
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Using complementary DNA prepared from adult chicken globin messenger RNA, we show the existence of 2-3 non-cross-hybridising globin sequences in the chicken genome, each of which is present in only one copy per haploid genome. This was done by solution hybridization to total DNA under conditions of cDNA excess. The data agreses with results of RNA-driven hybridisation of globin complementary DN...
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Gabriela Aguileta *, Joseph P. Bielawski 3,4 and Ziheng Yang 1 1 Department of Biology, University College London, Darwin Building, Gower Street, London WC1E 6BT, England 2 Linnaeus Centre for Bioinformatics, University of Uppsala, BMC, Box 598, 75124, Uppsala, Sweden 3 Department of Biology, Dalhousie University, Halifax, Nova Scotia, B3H 4J1, Canada 4 Department of Mathematics & Statistics, D...
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The widespread occurrence of intergenic transcription in eukaryotes is increasingly evident. Intergenic transcription in the beta-globin gene cluster has been described in murine and human cells, and models for a role in gene and chromatin activation have been proposed. In this study, we analyze intergenic transcription and the chromatin state throughout the human beta-globin gene cluster and f...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1986
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/14.17.7059